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The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine.
Cell Metab. 2021 May 4;33(5):905-922.e6. doi: 10.1016/j.cmet.2021.03.025. Epub 2021 Apr 21.
Cell Metab. 2021.
PMID: 33887198
Free PMC article.
Lifelong restriction of dietary branched-chain amino acids has sex-specific benefits for frailty and lifespan in mice.
Richardson NE, Konon EN, Schuster HS, Mitchell AT, Boyle C, Rodgers AC, Finke M, Haider LR, Yu D, Flores V, Pak HH, Ahmad S, Ahmed S, Radcliff A, Wu J, Williams EM, Abdi L, Sherman DS, Hacker T, Lamming DW.
Richardson NE, et al. Among authors: haider lr.
Nat Aging. 2021 Jan;1(1):73-86. doi: 10.1038/s43587-020-00006-2. Epub 2021 Jan 14.
Nat Aging. 2021.
PMID: 33796866
Free PMC article.
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